Acute hyperglycemia abolishes ischemic preconditioning: A possible mechanism for adverse outcome of patients with acute myocardial infarction and acute hyperglycemia
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چکیده
منابع مشابه
Acute hyperglycemia abolishes ischemic preconditioning in vivo.
Ischemic preconditioning provides a powerful means to reduce myocardial infarct size in vivo and has been proposed to limit the extent of myocardial infarction in patients. In contrast, hyperglycemia correlates with increases in mortality after acute myocardial infarction. Thus we hypothesized that acute hyperglycemia alters the protection afforded by ischemic preconditioning, and this hypothes...
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Stress hyperglycemia represents increased blood glucose level that is result of activation of neurohormonal processes in organism exposed to stress. The aim of the paper is to analyze literature data on prognostic implications of admission hyperglycaemia in patients with acute myocardial infarction (AMI). Retrospective study included 543 patients with AMI hospitalised in Department for cardiova...
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BACKGROUND Remote ischemic perconditioning (RIPerC) has a promising therapeutic insight to improve the prognosis of acute myocardial infarction. Chronic comorbidities such as diabetes are known to interfere with conditioning interventions by modulating cardioprotective signaling pathways, such as e.g., mTOR pathway and autophagy. However, the effect of acute hyperglycemia on RIPerC has not been...
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Managing Hyperglycemia in Acute Ischemic Stroke Patients To the Editor: The guidelines for the early management of adults with ischemic stroke1 published in the May 2007 issue of Stroke offer new recommendations regarding the management of hyperglycemia in this population. This is a very common problem, occurring in about one-third of nondiabetic and in most diabetic stroke patients,2 so the ca...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2003
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(03)82063-6